New Paper: “Unsupervised learning unravels the structure of four-arm and linear block copolymer micelles”

In our recent manuscript, we provide new fundamental insights into the microscopic structure of linear and four-arm block copolymers (members of the Pluronic and Tetronic families, respectively). The Pluronics and Tetronics typically self-assemble into small micelles in aqueous solution, which have found societally important applications in biomaterials and drug delivery. …

New Paper: “Interplay of lipid and surfactant: impact on nanoparticle structure”

In our recent manuscript we elucidate vital information into how the interactions between a surfactant and a lipid effect the internal structure and morphology of the nanoparticles that they form.  In doing so, we implement machine learning techniques alongside small angle neutron scattering experiments and molecular dynamics simulations to provide …

New Paper: “The impact of lipid digestion on the dynamic and structural properties of micelles”

In this manuscript, we elucidate the underlying molecular scale mechanisms which drive the changes in the dynamic and structural properties of phosphatidylcholine micelles as they are digested by the phospholipase A2 (PLA2) enzyme. Specifically, we have investigated micelles consisting of dihexanoylphosphatidylcholine (2C6PC) which have potential as drug delivery vehicles for …

Demi has been awarded the inaugural Jacky Pallas Memorial Award

Congratulations to Demi Pink for being awarded the inaugural Jacky Pallas Memorial Award.  This award is memory of Jacky Pallas, who passed away suddenly and unexpectedly earlier this year. Jacky was someone that I had the pleasure to interact with on several occasions in her role as head of e-Research …

New Paper: “On the structure of solid lipid nanoparticles”

In our recent manuscript entitled “On the structure of solid lipid nanoparticles“, we have combined large-scale all-atom molecular dynamics simulations and small angle neutron scattering (SANS) experiments to provide the first detailed description of the internal structure and atomistic interactions which govern this structure of liquid and solid lipid aggregates, …

My Biophysics In2ScienceUK Placement

(From 5 August until 16 August, we had the pleasure to have two young women, Sarah and Mariam, who are entering year 13, join our group for a summer placement sponsored by In2Science UK.  During their placement, Sarah and Mariam worked with Demi Pink on an aspect of her PhD …