New Paper: “Temporin B forms hetero-oligomers with temporin L, modifies its membrane activity, and increases the cooperativity of Its antibacterial pharmacodynamic profile”

In our most recent paper in collaboration with James Mason, David Phoenix & J. Mark Sutton, we have carried out a multi-disciplinary investigation of the synergistic effects of the antimicrobial peptides, temporin B & temporin L. The temporins comprise a very well-studied family of AMPs that now number more than …

New Paper: “A pleurocidin analogue with greater conformational flexibility, enhanced antimicrobial potency and in vivo therapeutic efficacy”

The 2016 Review on Antimicrobial Resistance (AMR) predicts that, unless action is taken, around 10 million deaths per year will be attributable to AMR by the year 2050. The pipeline of new antibiotics is limited, hence the potential of numerous alternatives to antibiotics – “noncompound approaches (i.e. products other than …