In this manuscript, we identify the underlying molecular scale mechanisms that drive the solubilisation of two different small molecule drugs within Triton X-114 surfactant micelles, and how the solubilisation affects the structural properties of the micelles. Specifically, we have investigated the solubilisation of the sodium salts of two different nonsteroidal …
In this work, we elucidate the underlying molecular scale mechanisms which drive the encapsulation of two different small molecule drugs within Triton X-100 surfactant micelles, and how the encapsulation effects the structural properties of the micelles. Specifically, we have investigated the encapsulation of two different nonsteroidal anti-inflammatory drugs (NSAIDs), ibuprofen …
Surfactant-covered aqueous interfaces are ubiquitous in everyday life. These interfaces play a key role in various commercial products, where surfactants adsorb onto the surface of bubbles or oil droplets to stabilize foams and emulsions. Examples of such foams and emulsions are commonly found in pharmaceuticals, detergents, cosmetics and lubricants. In …