In this manuscript, we present important findings on the transport of free protonated docosahexaenoic acid (DHAP) within a model a human brain lipid membrane and on the effect that DHAP has on the structural and dynamic properties of the membrane. We report the results of large-scale all-atom molecular dynamics simulations …
Phospholipids are a diverse group of biomolecules consisting of a hydrophilic headgroup and two hydrophobic acyl tails. The nature of the head and length and saturation of the acyl tails are important for defining the biophysical properties of lipid bilayers. It has recently been shown that the membranes of certain yeast …
In this manuscript, we present important findings of how lipid heterogeneity in model lipid membranes affect various structural and dynamic properties of the lipids within the membranes . We report the results of large-scale all-atom molecular dynamics simulations of commonly used simple model lipid membranes as well as two complex …