On Thursday 24th February, Sze May Yee successfully defended her PhD thesis entitled “Towards the Simulations of Complex Human Brain Cell Membranes.” May was examined by Edina Rosta and Antreas Kalli, who have requested that she completes minor corrections to her thesis. May’s viva was able to be held in …
In this work, we elucidate the underlying molecular scale mechanisms which drive the encapsulation of two different small molecule drugs within Triton X-100 surfactant micelles, and how the encapsulation effects the structural properties of the micelles. Specifically, we have investigated the encapsulation of two different nonsteroidal anti-inflammatory drugs (NSAIDs), ibuprofen …
Our project, entitled ‘DisCoVer: Aptamer biosensors for the detection of SARS-CoV-2 on surfaces’, is a collaboration between Dr Nunzianda Frascione and Dr James Gooch from the School of Population Health & Environmental Sciences and Professor Mark Green from the Department of Physics. Rob Ziolek is going to continue on working in the group as …
Our paper in which we reported the results of a multi-disciplinary investigation of the antimicrobial activity of protein pseudocapsids (ACS Nano (2020) 14, 1609-1622) has been recently recognised by the National Physics Laboratory with the awarding of the Rayleigh Award. For more information, read the King’s College London press release …
Jarvier Garcia-Ruiz has joined the Lorenz Lab as a PhD student. His studentship is funded by the National Physics Laboratory. During his PhD, Javier will be working in collaboration with Max Ryadnov at National Physics Laboratory and will be using molecular dynamics simulations to study self-assembled protein-based biomaterials. We are …
On Friday 12 November, Paul Smith successfully defended his PhD thesis entitled “Understanding Lipid Membrane Biophysics Through Molecular Simulation.” Paul was examined by Andela Saric and Arianna Fornili, who have requested that he completes minor corrections to his thesis. Paul’s viva was able to be held in a face-to-face setting, …
Miruna Serian has (re-)joined our group in order to do her PhD as part of the LIDo DTP PhD programme. In her PhD project, Miruna will be working with us and the group of James Mason in the Institute of Pharmaceutical Science at King’s College London. In her PhD, Miruna …
In this work, we demonstrate to atomic precision the structural origins of protein corona formation due to adsorption, driven only by the choice of functional groups on a graphitic material. Using graphene-oxide (GO) and double-clickable azide- and alkyne-double functionalised graphene oxide (C2GO) sheets, we study the adsorption of apolipoprotein c-3 …
In this manuscript, we present important findings on the transport of free protonated docosahexaenoic acid (DHAP) within a model a human brain lipid membrane and on the effect that DHAP has on the structural and dynamic properties of the membrane. We report the results of large-scale all-atom molecular dynamics simulations …
In our recent manuscript entitled “Effects of intercalated water on the lubricity of sliding layers under load:a theoretical investigation of MoS2” presents an original theoretical approach combining findings from ab-initio calculations (DFT) and classical molecular dynamics to provide an atomistic insight on the role of intercalated water in modifying frictional …